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вторник, 26 июня 2012 г.

New findings related to detection of testosterone use


Sportspersons become more and more sophisticated in usage of steroids. They study new methods to hide their usage of prohibited preparations. Several sportspersons spend time studying scientists’ conclusions which can help them to hide that they dope. Today a way has been found: sportspersons can mask usage of testosterone by drinking of green tea.
Testosterone is a hormone which is produced in body naturally. So, it can be difficult for anti-doping organizations to define that a sportsperson has taken testosterone. T: E ratio testing is commonly used by anti-doping agencies. Such tests can display uncommon ratio of testosterone to epitestosterone in urine. But it is not able to manifest difference between testosterone that has been created in body naturally and that introduced into body with the help of injections, creams, etc.
 Declan Naughton and his colleagues at Kingston University ( London) have determined that green tea contains such compounds that are called “catechins”. They have capacity to inhibit the enzyme UGT2B17. This enzyme promotes joining glucuronic acid to testosterone. In case UGT2B17 is inhibited, less testosterone glucoronide is excreted in urine.  
Catechins, the compounds that are able to mask administration of testosterone, are in green and white tea. Black tea lacks such compounds.
Naughton and his colleagues have conducted several experiments. They claim that a cup of strong green tea mask application of testosterone.
So, those sportspeople who use testosterone may decrease amounts of testosterone excreting in urine by consumption of green or white tea. Green or white tea can block excretion of testosterone, enhancing circulating levels of this hormone.
The World Anti-Doping Agency was informed about the findings by the scientists. If this process occurs, it is worthless to subject sportspersons to urine tests. Blood tests must be performed in order to detect usage of testosterone.
Olivier Rabin, the WADA’s specialist, confirms that regular checks of blood steroids will be added. Everything will be done by anti-doping agencies in order to avoid fooling of urine tests.

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